The Medicines Advice Service Evaluation

Not Applicable

Completed

• Conditions: Hyperlipidemias; Type 2 Diabetes
• Interventions: Other: Medicines Advice Service

• Registration Number: NCT01864239
• Lead Sponsor: University College, London

Brief Summary

The purpose of this study is to find out whether talking to a pharmacist on the telephone can help to support people taking medicine for a long-term condition.

Detailed Description

Non-adherence to medication is common and although some interventions have shown promise in improving adherence, the findings are inconsistent. This randomised controlled trial aims to test the effectiveness of a pharmacy-based telephone intervention compared to usual care on medication adherence and health outcomes in patients taking medicines for a long-term condition.

Study Timeline

• Study Start: 2012-11
• Study First Submitted: 2013-04-29
• Study First Submitted QC: 2013-05-23
• Study First Posted: 2013-05-29
• Primary Completion: 2014-09
• Study Completion: 2014-09
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-26
• Last Update Posted: 2015-05-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 677

Inclusion Criteria

• Patients prescribed medication(s) for at least one of the following conditions: type 2 diabetes, hyperlipidemia

Exclusion Criteria

• Patients living outside of England
• Patients with no access to a telephone
• Patients under the age of 18
• Patients unable to give written informed consent
• Patients on drugs for dementia
• Patients showing signs of dementia or cognitive impairment in conversation
• Patients with substantial hearing or sight impairment
• Patients whose medications are ordered by a caregiver/family member
• Patients with insufficient English to take part in the telephone intervention
• Patients living with someone already taking part in the study
• Patients newly prescribed a medication for the conditions listed in the inclusion criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Patient-centred tailored intervention	Medicines Advice Service	Medicines Advice Service

Primary Outcome Measures

Name	Time	Method
Self-reported medication adherence	6 months

Secondary Outcome Measures

Name	Time	Method
Prescription refill adherence	Baseline, 6 months and 12 months
Self-reported medicine-related problems and concerns	Baseline, 3 months and 6 months	Medicine-related problems and concerns will be assessed in a self-report questionnaire.
Beliefs about Medicines	Baseline, 3 months and 6 months	Beliefs about medicines will be assessed in a self-report questionnaire using the Beliefs About Medicines Questionnaire (BMQ) (Horne et al. 1999).
HbA1c	Baseline and 6 months
Serum Cholesterol Levels	Baseline and 6 months

Trial Locations

Locations (1)

UCL School of Pharmacy; 🇬🇧 London, United Kingdom