Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Language and Cognitive Function in Healthy Subjects
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Samsung Medical Center
- Enrollment
- 27
- Locations
- 1
- Primary Endpoint
- Verbal 3 back test
Study Overview
Brief Summary
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 19 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy subjects with age over 19 years old
Exclusion Criteria
- •history of disorders involving central nervous system
- •patients with severe medical or psychiatric disease
Arms & Interventions
Dual stimulation
i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex
Intervention: IFG stimulation (Device)
Dual stimulation
i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex
Intervention: DLPFC stimulation (Device)
IFG stimulation
anodal stimulation of left inferior frontal cortex
Intervention: IFG stimulation (Device)
DLPFC stimulation
anodal stimulation on left dorsolateral prefrontal cortex
Intervention: DLPFC stimulation (Device)
Sham stimulation
sham stimulation
Intervention: Sham stimulation (Device)
Outcomes
Primary Outcomes
Verbal 3 back test
Time Frame: Baseline and after intervention (approximately 30 minutes)
measure working memory
Korean Boston naming test
Time Frame: Baseline and after intervention (approximately 30 minutes)
measures naming ability thorough picture naming test
Secondary Outcomes
- Korean Color Word Stroop test(Baseline and after intervention (approximately 30 minutes))
- Controlled Oral Word Association Test(Baseline and after intervention (approximately 30 minutes))