Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Motor Function in Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Changes in motor evoked potential
研究概览
简要总结
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex, ii) anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 2) M1 stimulation: anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex; 3) PMC stimulation: anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 4) sham stimulation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects with age over 19 years old
排除标准
- •history of disorders involving central nervous system
- •patients with severe medial or psychiatric disease
研究组 & 干预措施
Dual stimulation
- anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex
- anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area
干预措施: M1 stimulation (Device)
M1 stimulation
anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex
干预措施: M1 stimulation (Device)
PMC stimulation
anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area
干预措施: PMC stimulation (Device)
Sham stimulation
Sham stimulation
干预措施: Sham stimulation (Device)
结局指标
主要结局
Changes in motor evoked potential
时间窗: Baseline and after intervention (approximately 30 minutes)
measure the motor threshold and amplitude of motor evoked potential in first dorsal interosseous muscle
次要结局
- Changes in sequential motor task(Baseline and after intervention (approximately 30 minutes))