Automated immuno phenotyping of neutrophils in geriatric hip fracture patients, the AQUIOS study
Completed
- Conditions
- broken hiphip fracture10005942
- Registration Number
- NL-OMON49050
- Lead Sponsor
- Sint Antonius Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
70 years old or above
Subtrochanteric, pertrochanteric, or femoral neck fracture
Exclusion Criteria
< 70 years
pathological fracture (i.e. suspect for malignancy)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is reached if the AQUIOS is started <30 minutes after<br /><br>blood withdraw and the flowcytometry data is saved in the computer. The study<br /><br>is defined as successful if het test is rightly done in >80% of all included<br /><br>patients.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary endpoints are defined as<br /><br>- a difference in protein expression and/or neutrophil responsiveness between<br /><br>the patients that develop infectious complications and patients who do not.<br /><br>- a difference in pH, PvO2, PvCO2, or HCO3- between the patients that develop<br /><br>infectious complications and patients who do not.</p><br>