Ventilation strategy in patients undergoing one lung ventilatio
Not Applicable
Completed
- Registration Number
- CTRI/2022/11/047212
- Lead Sponsor
- All India Institute Of Medical Sciences delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients undergoing elective thoracotomy surgery with OLV lobectomy metastatectomy esophagectomy chest wall resection surgery
ASA Physical Status I, II and III
Exclusion Criteria
Patients who do not give consent for the study
Patients with Body Mass Index (BMI) < 18.5 kg/m2 and > 35 kg/m2
Patients with moderate to severe derangements in Pulmonary Function Tests
Moderate to severe ARDS
Presence of bullae, pneumothorax in Chest Xray or CT scan
Severe COPD patients
COPD patients requiring oxygen therapy or CPAP
Previous lung resection surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the impact of alveolar recruitment followed by individualised PEEP on the oxygenation during and after OLVTimepoint: 24 hours from surgery
- Secondary Outcome Measures
Name Time Method Change in driving pressure, plateau pressure, peak pressure at selected time pointsTimepoint: 24 hours from surgery;Change in haemodynamic parameters PPV MAP HR SpO2Timepoint: T1 5 minutes after induction supine TLV <br/ ><br>T2 lateral decubitus, OLV 30 minutes after recruitment and PEEP titration <br/ ><br>T3 at the end of OLV TLV supine after recruitment and re-PEEP titration <br/ ><br>;Change in pH, PaO2, PCO2, lactate at selected time pointsTimepoint: T1 5 minutes after induction, supine, TLV <br/ ><br>T2 lateral decubitus, OLV 30 minutes after recruitment and PEEP titration <br/ ><br>T3 at the end of OLV TLV supine, after recruitment and re-PEEP titration <br/ ><br>;Post-operative pulmonary complicationsTimepoint: 30 days from surgery