High Intensity Interval Training on Overweight and Obese Individuals and its effect on Insulin Sensitivity: A Pre and Post Study.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- ICMR
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Venous blood samples will be collected following a 12hr overnight fast at baseline and post-intervention Fasting Glucose levels will be analyzed using hexokinase method and Fasting Insulin levels will be analysed using Electrochemiluminiscence immunoassay
Study Overview
Brief Summary
The study’s outcomes will suggest that incorporating just 30 minutes of high-intensity interval training (HIIT) into regular exercise routines can significantly improve cardiorespiratory fitness in overweight and obese individuals. This has important public health implications, as it provides an efficient, time-effective intervention for improving cardiovascular health and potentially reducing the risk of chronic diseases associated with obesity. Moreover, it highlights HIIT as a viable alternative to longer-duration moderate-intensity workouts, which may enhance adherence among individuals with limited time or motivation
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18.00 Year(s) to 50.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Adults aged 18-50 years.
- •Body Mass Index (BMI) greater than or equal to 23 kg/m² (overweight) or greater than or equal to 27 kg/m² (obese) according to Extended International (IOTF) Body Mass Index Cut-Offs.
- •Sedentary lifestyle (any waking behavior characterized by an energy expenditure of 1.5 METs or less while in a sitting, reclining, or lying posture) (Physical Activity Guidelines Advisory Committee, 2018).
- •Ability to provide informed consent.
- •Medical clearance for high-intensity exercise participation.
Exclusion Criteria
- •Diagnosed cardiovascular disease, uncontrolled hypertension (greater than 160/100 mmHg), or cardiac arrhythmias.
- •Type 1 diabetes mellitus or insulin-dependent Type 2 diabetes mellitus.
- •Musculoskeletal injuries or conditions limiting exercise participation.
- •Pregnancy or lactation.
- •Current participation in structured exercise programs.
- •Use of medications significantly affecting glucose metabolism (excluding stable doses of metformin).
- •Recent weight loss surgery (less than 12 months) or current enrollment in weight loss programs.
Outcomes
Primary Outcomes
Venous blood samples will be collected following a 12hr overnight fast at baseline and post-intervention Fasting Glucose levels will be analyzed using hexokinase method and Fasting Insulin levels will be analysed using Electrochemiluminiscence immunoassay
Time Frame: screening anthropometric measurements body composition analysis Insulin Sensitivity Muscle mass will be recorded at Baseline week 0 visit 1 and post 48 hours Visit 2 Post intervention assessment similar to baseline procedures at Week 9
Secondary Outcomes
- Anthropometric measurements: height, weight, BMI, waist circumference(- Resting heart rate & blood pressure)
Investigators
Prachitha D M
JSSAHER, Mysuru