High Intensity Interval Training on Overweight and Obese Individuals and its effect on Insulin Sensitivity: A Pre and Post Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- ICMR
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Venous blood samples will be collected following a 12hr overnight fast at baseline and post-intervention Fasting Glucose levels will be analyzed using hexokinase method and Fasting Insulin levels will be analysed using Electrochemiluminiscence immunoassay
研究概览
简要总结
The study’s outcomes will suggest that incorporating just 30 minutes of high-intensity interval training (HIIT) into regular exercise routines can significantly improve cardiorespiratory fitness in overweight and obese individuals. This has important public health implications, as it provides an efficient, time-effective intervention for improving cardiovascular health and potentially reducing the risk of chronic diseases associated with obesity. Moreover, it highlights HIIT as a viable alternative to longer-duration moderate-intensity workouts, which may enhance adherence among individuals with limited time or motivation
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Adults aged 18-50 years.
- •Body Mass Index (BMI) greater than or equal to 23 kg/m² (overweight) or greater than or equal to 27 kg/m² (obese) according to Extended International (IOTF) Body Mass Index Cut-Offs.
- •Sedentary lifestyle (any waking behavior characterized by an energy expenditure of 1.5 METs or less while in a sitting, reclining, or lying posture) (Physical Activity Guidelines Advisory Committee, 2018).
- •Ability to provide informed consent.
- •Medical clearance for high-intensity exercise participation.
排除标准
- •Diagnosed cardiovascular disease, uncontrolled hypertension (greater than 160/100 mmHg), or cardiac arrhythmias.
- •Type 1 diabetes mellitus or insulin-dependent Type 2 diabetes mellitus.
- •Musculoskeletal injuries or conditions limiting exercise participation.
- •Pregnancy or lactation.
- •Current participation in structured exercise programs.
- •Use of medications significantly affecting glucose metabolism (excluding stable doses of metformin).
- •Recent weight loss surgery (less than 12 months) or current enrollment in weight loss programs.
结局指标
主要结局
Venous blood samples will be collected following a 12hr overnight fast at baseline and post-intervention Fasting Glucose levels will be analyzed using hexokinase method and Fasting Insulin levels will be analysed using Electrochemiluminiscence immunoassay
时间窗: screening anthropometric measurements body composition analysis Insulin Sensitivity Muscle mass will be recorded at Baseline week 0 visit 1 and post 48 hours Visit 2 Post intervention assessment similar to baseline procedures at Week 9
次要结局
- Anthropometric measurements: height, weight, BMI, waist circumference(- Resting heart rate & blood pressure)