Psychosocial Outcomes and Transition Readiness in JIA

Completed

• Conditions: Juvenile Idiopathic Arthritis

• Registration Number: NCT04216498
• Lead Sponsor: Sheffield Children's NHS Foundation Trust

Brief Summary

It is widely acknowledged that the transition from paediatric to adult health services should be a multidimensional and multidisciplinary process that addresses the medical, psychosocial, and educational needs of adolescents and young adults (AYA). Despite this, there is currently a scarcity of research examining the relationships between psychosocial factors (e.g., anxiety, social support) and transition readiness in AYA with juvenile idiopathic arthritis (JIA). This study therefore aimed to examine the relationships between psychosocial factors and transition readiness in pre-transfer adolescents and post-transfer young adults aged 10-25 years diagnosed with JIA at a single centre.

In total, 40 adolescents aged 10-16 years together with a parent/guardian, will take part at Sheffield Children's Hospital and 40 young adults aged 16-25 years will take part at Sheffield Teaching Hospitals. Participants will be asked to complete a battery of self-report questionnaire measuring psychosocial factors (anxiety/depression, social support, family functioning, health-related quality of life) and transition readiness (transition knowledge and skills, self-efficacy). JIA disease severity was also measured during clinic appointments. This study has received full ethical approval, and all participants will give their written informed assent or consent before taking part.

The results from this research will be important in better understanding which psychosocial factors affect how ready young people with JIA feel to move from paediatric to adult rheumatology services. We hope this research will inform further work to help target psychological interventions in this group of patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-24
• Primary Completion: 2018-04-18
• Study Completion: 2018-04-18
• Study First Submitted: 2018-05-21
• Status Verified: 2019-12
• Study First Submitted QC: 2019-12-31
• Last Update Submitted: 2019-12-31
• Study First Posted: 2020-01-02
• Last Update Posted: 2020-01-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Aged 10-25 years
• Diagnosis of juvenile idiopathic arthritis (including all ILAR subtypes except 'systemic arthritis' and 'undifferentiated arthritis')
• Juvenile idiopathic arthritis managed by Sheffield Children's Hospital or Sheffield Teaching Hospitals
• Fluent in verbal and written English

Patient

Exclusion Criteria

• Aged <10 years or >25 years
• Diagnosis of juvenile idiopathic arthritis ILAR subtypes 'systemic arthritis' or 'undifferentiated arthritis')
• Diagnosis of uveitis
• Non-fluent in verbal and written English

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Generalised Anxiety	1 day	Generalised Anxiety Disorder-7 Questionnaire (Spitzer et al., 2006)

Secondary Outcome Measures

Name	Time	Method
Depression	1 day	Patient Health Questionnaire-9 Questionnaire (Spitzer et al., 1999)
Health-related quality of life	1 day	Paediatric Quality of Life Arthritis Module (Varni et al., 2002)
Social support	1 day	Bath Adolescent Pain Questionnaire Social Support Subscale (Eccleston et al., 2005)
Family functioning	1 day	Bath Adolescent Pain Questionnaire Family Functioning Subscale (Eccleston et al., 2005)
Prosocial and problem behaviours	1 day	Strengths and Difficulties Questionnaire (Goodman, 1997)
JIA disease severity (JADAS-3)	1 day	JADAS-3 is a composite score of patient VAS score, physician VAS score, active joint count

Trial Locations

Locations (1)

Sheffield Children's NHS Foundation Trust; 🇬🇧 Sheffield, United Kingdom