STEP study.
Completed
- Conditions
- osocomial Staphylococcus aureus infection.
- Registration Number
- NL-OMON28142
- Lead Sponsor
- Primary sponsor:Department of Medical Microbiology and Infectious Disease at Erasmus MC, University Medical Center, Rotterdam, the Netherlands.Secondary sponsors:Canisius Wilhelmina hospital, Nijmegen, the NetherlandsAmphia hospital, Breda, the NetherlandsUniversity Medical Center Utrecht, Utrecht, the NetherlandsVU Medical Center, Amsterdam, the Netherlands
- Brief Summary
CDC definitions for nosocomial infections. J.S. Garner et al. In: Olmsted RN, ed.: APIC Infection control and applied epidemiology: Principles and practice. St. Louis: Mosby; 1996:pp A-1--A-20. Mupirocin prophylaxis against nosocomial Staphylococcus aureus infections in nonsurgical patients. A randomized study. H.F.L. Wertheim et al. Ann Intern Med 2004;140:419-25.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1800
Inclusion Criteria
1. Adult patients (>= 18 years);
2. Rapid detection positive for S. aureus nasal carriage;
Exclusion Criteria
1. S. aureus infection at enrollment;
2. Allergy to mupirocin;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method osocomial S. aureus infection until 6 weeks after discharge according to CDC-criteria.
- Secondary Outcome Measures
Name Time Method 1. Duration of hospital stay;<br /><br>2. In-hospital mortality;<br /><br>3. Time to nosocomial S. aureus infection.