The Bristol Meningococcal Natural History of Carriage study

Not Applicable

Completed

• Conditions: Topic: Children; Subtopic: All Diagnoses; Disease: All Diseases; Not Applicable

• Registration Number: ISRCTN98439755
• Lead Sponsor: niversity of Bristol

Brief Summary

2021 Results article in https://doi.org/10.1016/S1473-3099(20)30842-2 (added 18/02/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-04-14
• Study Completion: 2017-06-30
• Last Update Posted: 1 March 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

The study will recruit healthy male and female students aged 15 to 19 years attending participating schools/colleges in Bristol who are enrolled in the Wellcome Trust funded cross-sectional meningococcal carriage study, and whose consent for that study included agreement to potentially be re-approached concerning this study. All subjects must provide signed informed consent to participate in this longitudinal study.
Target Gender: Male & Female; Upper Age Limit 19 years ; Lower Age Limit 15 years

Exclusion Criteria

Any medical condition or circumstances which, in the opinion of the investigator, will jeopardise the likelihood of safe or effective participation in the study

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Distribution of carriage density; Timepoint(s): At entry and over the course of the study

Secondary Outcome Measures

Name	Time	Method
<br> 1. Acquisition of carriage; Timepoint(s): rates over the course of the study<br> 2. Duration of carriage; Timepoint(s): Over the course of the study<br> 3. Patterns of carriage; Timepoint(s): heterogeneity over study period between subgroups, especially high density and long duration carriage<br>