CHO-loading Before and High Intermittent CHO-intake During Physical Exercise in T1D
- Conditions
- Diabetes Mellitus, Type 1
- Interventions
- Other: Carbohydrate loading and high intermittent carbohydrate intake during physical exercise
- Registration Number
- NCT03722225
- Lead Sponsor
- Örebro University, Sweden
- Brief Summary
Prolonged physical exercise (PE) is a challenge in type 1 diabetes with an increased incidence of both hypoglycemia and hyperglycemia.
The purpose was to evaluate the impact of two consecutive days of carbohydrate (CHO) loading, followed by high intermittent CHO-intake during prolonged PE, facilitated by a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM), on glucose control in individuals with type 1 diabetes.
Ten physically active individuals with type 1 diabetes were invited to participate in a 3-day long sports camp with the objective to evaluate CHO-loading and high intermittent CHO-intake during prolonged PE. 1.5 months later the same procedure was evaluated during a 90 km cross-country skiing race. Participants were instructed to act proactively using rtCGM with predictive alerts set for high and low glucose values to maintain sensor glucose values within target range, defined as 72-180 mg/dl (4-10 mmol/l).
- Detailed Description
This is a descriptive, single arm, non-randomized interventional study. The intervention consisted of carbohydrate loading prior to and intermittent high carbohydrate intake during physical exercise and a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM) to achieve and maintain glucose control.
Central Contact Person Stig A Mattsson, dietician PhD student Phone: +46702047759 E-mail: stigmattsson@live.com
IPD Sharing Statement No: There is not a plan to make IPD available.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Not provided
- A1c 8.6% NGSP (70 mmol/mol IFCC)
- proliferative retinopathy
- known nephropathy
- cardiac failure
- following a low-carbohydrate diet.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Descriptive, single arm, interventional study Carbohydrate loading and high intermittent carbohydrate intake during physical exercise The intervention consisted of carbohydrate loading prior to and intermittent high carbohydrate intake during physical exercise and a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM) to achieve and maintain glucose control
- Primary Outcome Measures
Name Time Method The percentage of the glucose values spent in target range, defined as 72-180 mg/dl. Through 48 hours of carbohydrate loading and an average of 6.5 hours of cross-country skiing.
- Secondary Outcome Measures
Name Time Method