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临床试验/NCT06059911
NCT06059911进行中(未招募)不适用

The Effect of a Pre-workout Supplement on Basketball-specific Performance and Biochemical Profile of Well-trained Athletes

Athanasios Z. Jamurtas1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2022年6月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
36
试验地点
1
主要终点
Urea concentration

研究概览

简要总结

Pre-workout supplements (PWS) consumption in recreationally or physically trained males lead to many performance-enhancing benefits, including improvements in mean power output during single and repeated sprints, agility, reaction times, lower body muscular endurance and reduced fatigue. PWS ingestion also improves anaerobic performance and prolongs time to exhaustion during high-intensity intermittent exercise. However, PWSs' effectiveness is not constant, as they do not alter anaerobic power, jumping performance or blood lactate concentrations after a training session, at least in recreationally trained males and strength-power athletes. Moreover, the effects of long-term PWS supplementation, where some nutritional agents were combined (e.g., β-alanine, creatine, citrulline malate, etc.) to assess endurance-trained runners or elite cyclists' performance, are mixed and less clear. Even though the popularity of PWS use has increased among trained/professional athletes, most of the data in this area are derived from recreationally and not from well-trained athletes of a competitive level (especially in team sports). Therefore, the present study aimed to examine the acute and chronic effects of a PWS, containing 200 mg caffeine, 3.3 g creatine monohydrate, 3.2 g βalanine, 6 g citrulline malate and 5 g BCAA per dose, on shooting, jumping, sprinting, agility, aerobic and anaerobic performance in well-trained basketball players.

详细描述

According to a randomized, double-blind, placebo-controlled, research design, 36 well-trained male basketball players will be recruited. During their first visit, they will complete a health history and exercise questionnaire and will sign a written informed consent. Participants' dietary profile will be evaluated using 3- day diet recalls and they will be instructed to follow the same dietary scheme for 3 days prior to the subsequent evaluations. During the second visit, participants will be familiarized with the performance evaluations (shooting, jumping, sprinting, agility, running-based anaerobic sprint test and Yo-Yo intermittent recovery level 1 test).

(Acute phase) One week later, Moreover, they will randomly be assigned in two groups (PWS and placebo) by a research member not involved in data collection. After that participants will visit the basketball court in the morning and a blood sample will be collected after overnight fasting. Afterward, the participants in each group will perform the evaluations without PWS or PL. The evaluations will be performed according to National Strength and Conditioning Association standards. Body composition, resting heart rate, blood pressure, basketball-specific shooting exercise, counter-movement jump, 20-m sprint, agility T-Test, running-based anaerobic sprint test and Yo-Yo intermittent recovery level 1 test. One week later, all participants will visit the same basketball court at the same hour and will consume the PWS or placebo supplement and 30 minutes later their physiological characteristics and performance will be evaluated in the same sequence.

(Chronic phase) Following the evaluations of the acute phase, participants will continue the consumption of the PWS or placebo, according to their allocation group, daily for a period of 4 weeks. At the end of the supplementation period, participants will visit the basketball court and a second blood sample will be collected after overnight fasting (the first blood sample, collected before the acute phase evaluations, will serve as baseline). Then, participants' performance will be evaluated in the same sequence as the previous visit.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 41 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •Male participants, 18-41 years old
  • •Absence of drugs, abuse or medications, which are known to affect the Shooting, sprinting, jumping, agility, anaerobic and endurance performance
  • •Consent to follow a regular dietary plan for basketball players

排除标准

  • •Restraining orthopedic/neuromuscular problems
  • •Caffeine hypersensitivity
  • •Consumption of more than three servings of coffee per day
  • •Use of any supplement or steroids prior to the study
  • •Use of creatine, β-alanine, citrulline malate or BCAA-protein supplementation at least six months before the initiation of the study

研究组 & 干预措施

Multi-ingredient dietary supplement

Experimental

20 g of a multi-ingredient dietary supplement. Composition: 200 mg caffeine, 3.3 g creatine monohydrate, 3.2 g β-alanine, 6 g citrulline malate and 5 g BCAA

干预措施: Multi-ingredient dietary supplement (caffeine, creatine monohydrate, β-alanine, citrulline malate, BCAA) (Dietary Supplement)

Placebo dietary supplement (97% maltodextrin)

Placebo Comparator

20 g of isoenergetic placebo dietary supplement. Composition: 97% flavored maltodextrin, similar in color, flavor, taste and energy to the experimental multi-ingredient supplement

干预措施: Placebo dietary supplement (97% maltodextrin) (Dietary Supplement)

结局指标

主要结局

Urea concentration

时间窗: baseline and up to 4 weeks

Urea will be measured on a clinical chemistry analyzer

Rate of basketball-specific shooting performance

时间窗: baseline and up to 4 weeks

Basketball-specific shooting performance will be evaluated with a test consisting of 30 free shoots, 30 middle-distance shoots and 30 long-distance shoots

Blood lactate concentartion

时间窗: baseline and up to 4 weeks

Blood lactate concentration will be measured using a portable blood lactate analyzer

Creatinine concentration

时间窗: baseline and up to 4 weeks

Creatinine will be measured on a clinical chemistry analyzer

Rate of agility T-test performance

时间窗: baseline and up to 4 weeks

Agility T-test will be evaluated using photocell gates

Rate of running-based anaerobic sprint test performance

时间窗: baseline and up to 4 weeks

Running-based anaerobic sprint test performance will be evaluated using photocell gates

Serum glutamic-oxaloacetic transaminase activity

时间窗: baseline and up to 4 weeks

Serum glutamic-oxaloacetic transaminase will be measured on a clinical chemistry analyzer

Serum glutamate-pyruvate transaminase activity

时间窗: baseline and up to 4 weeks

Serum glutamate-pyruvate transaminase will be measured on a clinical chemistry analyzer

Countermovement jump height

时间窗: baseline and up to 4 weeks

Jumping performance will be evaluated using a contact platform

20 meters sprint running time

时间窗: baseline and up to 4 weeks

Sprint performance will be evaluated using photocell gates

Rate of Yo-Yo intermittent recovery test level 1 test performance

时间窗: baseline and up to 4 weeks

Yo-Yo intermittent recovery test level 1 test performance will be evaluated using a field-based test

Lactate dehydrogenase concentration

时间窗: baseline and up to 4 weeks

Lactate dehydrogenase will be measured on a clinical chemistry analyzer

Alkaline phosphatase concentration

时间窗: baseline and up to 4 weeks

Alkaline phosphatase will be measured on a clinical chemistry analyzer

Creatine kinase concentration

时间窗: baseline and up to 4 weeks

Creatine kinase activity will be measured on a clinical chemistry analyzer

Gamma-glutamyltransferase concentration

时间窗: baseline and up to 4 weeks

Gamma-glutamyltransferase will be measured on a clinical chemistry analyzer

次要结局

  • Systolic and diastolic blood pressure(baseline and up to 4 weeks)
  • Body mass(baseline and up to 4 weeks)
  • Body height(baseline and up to 4 weeks)
  • Heart rate(baseline and up to 4 weeks)
  • Body fat mass(baseline and up to 4 weeks)

研究者

发起方
Athanasios Z. Jamurtas
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Athanasios Z. Jamurtas

Professor

University of Thessaly

研究点 (1)

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