Can Egg Allergic Kids Eat Baked Egg? The CAKE Study.

Not Applicable

• Conditions: Egg Allergy; Inflammatory and Immune System - Allergies

• Registration Number: ACTRN12612000173897
• Lead Sponsor: Women's and Children's Health Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-02-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

IgE mediated egg allergy
Positive oral food challenge to pasteurised raw egg.
Tolerance to baked egg.

Exclusion Criteria

Inability to provide informed consent.
Non IgE mediated egg allergy.
Children already consuming baked egg in their diet.
FPIES, Wheat allergy.
Children with any congenital or acquired disease or developmental disorder likely to affect the ablility to undergo an oral food challenge or to consume the intervention product.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Raw Egg Challenge[At baseline and after 6 months of intervention.]

Secondary Outcome Measures

Name	Time	Method
Blood test to measure immune markers of tolerance development (serum specific IgE, IgG & IgG4, and cellular immune response profiles).[At baseline and at 6 months when intervention is ceased, and then again at 7 months prior to raw egg challenge.]