on invasive investigation of the underlying cause of differences in metabolic capacity along the length of the tibialis anterior muscle using Magnetic Resonance

Completed

• Conditions: N/A; 10028396; 10018424; 10028302

• Registration Number: NL-OMON43213
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

- healthy
- male
- Age between 18-35 years
- BMI between 19 and 25 kg/m2
- MR eligibility; verified using a questionnaire

Exclusion Criteria

- MR ineligibility; verified using a questionnaire
-- inability to lay supine for 90 minutes

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the exercise PCr decline and post exercise<br /><br>recovery, potential splitting of Pi peaks, end-exercise pH, muscle perfusion<br /><br>via MRI and NIRS.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>A secondary study parameter is the local strain measured with ultrasound.</p><br>