Analysis of clinical features and prognosis of anti-neutrophil cytoplasmic antibody-associated vasculitis
Not Applicable
- Conditions
- anti-neutrophil cytoplasmic antibody associated vasculitis
- Registration Number
- JPRN-UMIN000036873
- Lead Sponsor
- Jichimedical University
- Brief Summary
The multivariable Cox proportional hazards regression analysis showed that age over than 65: HR 1.69, 95 percent CI 1.07 to 2.81, p equal 0.025, performance status of 3 to 4: HR 1.98, 95 percent CI 1.21 to 3.23, p equal 0.008, cumulative dose of prednisolone over than 1,500mg : HR 2.21, 95 percent CI 1.37 to 3.81, p lower than 0.001, and oral cyclophosphamide: HR 1.84, 95 percent CI 1.13 to 3.00, p equal 0.016 were independent risk factors for immunosuppressant discontinuation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 162
Inclusion Criteria
Not provided
Exclusion Criteria
none
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study outcomes of relapses, occurrences of adverse events, discontinuing of immunosuppressants, and survival rate, for five years.
- Secondary Outcome Measures
Name Time Method