Abdominal Muscle Thickness in Mechanically Ventilated Patients During Spontaneous Breathing Trials
试验速览
- 阶段
- 不适用
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Correlation between thickening fraction and SBT outcome
研究概览
简要总结
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated patients. In addition the reliability of the sonographic measurements will be assessed.
详细描述
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated patients. In addition the reliability of the sonographic measurements will be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •greater than 18 years old
- •Patients requiring invasive mechanical ventilation including patients with endotracheal tube and tracheotomies
排除标准
- •Patients with a previously diagnosed neuromuscular disorder (acute or chronic)
- •Behavioural agitation
- •Patients who are not awake and cooperative
- •Previously enrolled in the study
结局指标
主要结局
Correlation between thickening fraction and SBT outcome
时间窗: Measurements will be performed before SBT
Correlation between thickening fraction of each muscles evaluated by ultrasound before the SBT and the SBT outcome.
次要结局
- Correlation between the pressures generated by respiratory muscles and SBT outcome(Measurements will be performed before SBT)
- Inter-rater agreement(Measurements will be performed before SBT)
研究者
Piva Simone
Dr. Piva Simone, M.D.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia