Changes in Cerebral Oxygenation Related to Intraoperative Position Changes
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in cerebral oxygenation at 30 degrees
研究概览
简要总结
This is a prospective, observational study. This study will assess the effect of temporary changes in body position (supine, head of bed elevated 30 degrees, head of bed elevated 60 degrees) in anesthetized patients. Tissue oxygenation will be assessed non-invasively using near infrared spectroscopy (NIRS) by a device that is used in our operating rooms and the ICU setting to assess cerebral and tissue oxygenation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 21 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 10-21 years of age undergoing posterior spinal fusion, requiring neurophysiologic monitoring and an arterial cannula
排除标准
- •Patients in whom an arterial cannula is not indicated for the surgical procedure
- •Patients with comorbid conditions that may impact cerebral blood flow, cerebral perfusion or place them at risk for cerebral hypoperfusion
- •Patients in whom an invasive arterial cannula cannot be placed
结局指标
主要结局
Change in cerebral oxygenation at 30 degrees
时间窗: 5-10 minutes after start of study
Moving the head of the bed to 30 degrees and comparing cerebral oxygen levels to levels when patient was lying flat.
Change in cerebral oxygenation at 60 degrees
时间窗: 10-15 minutes after start of study
Moving the head of the bed to 60 degrees and comparing cerebral oxygen levels to levels when patient was lying flat.
次要结局
未报告次要终点
研究者
Joseph D. Tobias
Chief - Department of Anesthesiology and Pain Medicine
Nationwide Children's Hospital