Efficacy of early Helicobacter Pylori eradication versus continuous pantoprazol Infusion in prevention of rebleeding in peptic ulcer patients

Phase 3

• Conditions: Peptic ulcer-GI bleeding.; Gastric ulcer -Duodenal ulcer -Acute with haemorrhage; k25-k26

• Registration Number: IRCT201108073836N2
• Lead Sponsor: Jundishapour Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

The bleeding peptic ulcer patients with age = 16 y old who have stigmata of recent bleeding like active spurting ( Forrest IA), non bleeding visible vessel ( Forrest IIA), oozing or adherent clot with visible vessel ( Forrest IA, IB, IIA) will be included in study. The exclusion criteria are: esophageal varicose, liver cirrhosis, malignancy, concomitant morbidity, cardiac pacemaker, NSAID consumption, current therapy with anti coagulant, antibiotic or PPI and multiple ulcers.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Surgery. Timepoint: One Week. Method of measurement: Number.;Transfustion. Timepoint: One week. Method of measurement: Number.;Mortality. Timepoint: One week. Method of measurement: Number.;Duration of admission. Timepoint: One week. Method of measurement: Day.;Rebleeding. Timepoint: One week. Method of measurement: Hematemesis, Repeating melena, >2gr/dl Decrease in Hb level, Pulse rate > 90/min or sudden drop in blood pressure.

Secondary Outcome Measures

Name	Time	Method
Rebleeding. Timepoint: 0ne month. Method of measurement: Hematemesis, Repeating melena, >2gr/dl Decrease in Hb level, Pulse rate > 90/min or sudden drop in blood pressure.;Surgery. Timepoint: One month. Method of measurement: Number.;Transfustion. Timepoint: One month. Method of measurement: Number.;Mortality. Timepoint: One month. Method of measurement: Number.;Duration Admission. Timepoint: One month. Method of measurement: Day.