Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria

• Conditions: ARDS; High Altitude

• Registration Number: NCT04199650
• Lead Sponsor: Southeast University, China

Brief Summary

The severity stratification criteria for acute respiratory distress syndrome (ARDS) in Xi'ning Qinghai province (mean altitude: 2200m) were clarified according to the oxygenation index (PaO2/FiO2).

Detailed Description

This study is a single-center retrospective study. According to the Berlin diagnostic standard, ARDS patients admitted to the Department of severe Medicine, affiliated Hospital of Qinghai University from January 2018 to December 2018 were divided into three groups: mild (153mmHg \< PaO2/ FiO2 ≥ 230 mmHg), moderate (76mmHg \< PaO2/ FiO2 ≥ 153 mmHg) and severe (PaO2/ FiO2 ≥ 76 mmHg). The ICU mortality, 28-day mortality, non-ventilator time in ICU, ICU hospitalization time and non-I hospitalization were observed respectively. The difference of CU time and total hospitalization days.

Study Timeline

• Study Start: 2019-04-01
• Status Verified: 2019-12
• Study First Submitted: 2019-12-05
• Study First Submitted QC: 2019-12-13
• Last Update Submitted: 2019-12-13
• Study First Posted: 2019-12-16
• Last Update Posted: 2019-12-16
• Primary Completion: 2020-01-30
• Study Completion: 2020-08-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 253

Inclusion Criteria

• 18 years of age
• Meet the diagnostic criteria of ARDS
• Receive invasive mechanical ventilation

Exclusion Criteria

• Receive a large number of hormone shock therapy in a short period of time
• Death within a short period of time (< 24 h) after mechanical ventilation
• No chest imaging data
• Data missing

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28-days mortality rate	28 days after discharge	Mortality at 28 days of hospitalization
ICU mortality	up to 24 weeks	Mortality during treatment in ICU

Secondary Outcome Measures

Name	Time	Method
Hospital length of stay	up to 24 weeks	Total length of stay in hospital
Ventilator Free time	up to 24 weeks	Ventilator time not used in ICU
Ventilator time	up to 24 weeks	Ventilator time in ICU

Trial Locations

Locations (1)

ChunPan; 🇨🇳 Nanjing, Jiangsu, China