Definition of Acute Respiratory Distress Syndrome in Plateau of Qinghai in China: Verification of Berlin Definition Plateau Criteria
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 253
- 试验地点
- 1
- 主要终点
- 28-days mortality rate
研究概览
简要总结
The severity stratification criteria for acute respiratory distress syndrome (ARDS) in Xi'ning Qinghai province (mean altitude: 2200m) were clarified according to the oxygenation index (PaO2/FiO2).
详细描述
This study is a single-center retrospective study. According to the Berlin diagnostic standard, ARDS patients admitted to the Department of severe Medicine, affiliated Hospital of Qinghai University from January 2018 to December 2018 were divided into three groups: mild (153mmHg < PaO2/ FiO2 ≥ 230 mmHg), moderate (76mmHg < PaO2/ FiO2 ≥ 153 mmHg) and severe (PaO2/ FiO2 ≥ 76 mmHg). The ICU mortality, 28-day mortality, non-ventilator time in ICU, ICU hospitalization time and non-I hospitalization were observed respectively. The difference of CU time and total hospitalization days.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age
- •Meet the diagnostic criteria of ARDS
- •Receive invasive mechanical ventilation
排除标准
- •Receive a large number of hormone shock therapy in a short period of time
- •Death within a short period of time (< 24 h) after mechanical ventilation
- •No chest imaging data
- •Data missing
结局指标
主要结局
28-days mortality rate
时间窗: 28 days after discharge
Mortality at 28 days of hospitalization
ICU mortality
时间窗: up to 24 weeks
Mortality during treatment in ICU
次要结局
- Hospital length of stay(up to 24 weeks)
- Ventilator Free time(up to 24 weeks)
- Ventilator time(up to 24 weeks)
研究者
Chun Pan
Deputy chief physician
Southeast University, China