A clinical trial to evaluate and compare the level of nitric oxide in serum and saliva of smokers and non smokers with periodontal disease before and after oral hygiene measures ( professional teeth cleaning) .

Phase 1

Completed

• Registration Number: CTRI/2016/01/006511
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Individuals with a minimum of 20 teeth will be enrolled in the study.

1.Group I

a.Chronic periodontitis patients with more than 30% of sites with the presence of a PPD of >= 5mm and CAL of >= 5mm.

b.Patients with no history of smoking.

2.Group II

a.Chronic periodontitis patients with more than 30% of sites with the presence of a PPD of >= 5mm and CAL of >= 5mm.

b.Patients with history of smoking at least 10 cigarettes per day for the last 3 years.

Exclusion Criteria

Exclusion Criteria:

1.Pregnant women or lactating mothers.

2.Subjects who have undergone any periodontal therapy in the past 6 month.

3.Subjects on antibiotics, anti-inflammatory therapy, or vitamin/nutritional supplements.

4.Subjects with systemic diseases such as diabetes mellitus, hyperten-sion, renal disease, rheumatoid arthritis, periapical infection of any tooth, or any other form of systemic inflammatory in¬volvement

Study & Design

• Study Type: Interventional
• Study Design: Not specified