Vitamin D and Cognition Trial

Phase 3

Recruiting

• Conditions: Mild Cognitive Impairment and vitamin D (25-hydroxyvitamin D) blood concentration between 50 nmol/L and 12.5 nmol/L.; Mental Health - Studies of normal psychology, cognitive function and behaviour; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12607000321448
• Lead Sponsor: Professor Nicola Lautenschlager

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-06-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Adults with mild cognitive impairment (-1.5 standard deviations below norm on any task in the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) neuropsychological battery), over 65 years of age, Vitamin D concentration between 12.5 and 50 nmol/L at baseline.

Exclusion Criteria

Diagnosis of osteoporosis requiring treatment, no informant available, severe physical or medical illness that would preclude completion of the trial, hearing or visual impairment that would preclude assessments, already in an intervention trial, clinical history of stroke, fall in the last 3 months, heart attack in the last 3 months, fall with fracture over the age of 65, history of kidney or bladder stones, current acute depression, history of schizophrenia, current diagnosis of dementia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive Decline as measured by the Cambridge Examination for mental disorders in the Elderly - Cognitive section (CAMCOG) [Measured at 6, 12, and 18 month follow-up.]