Changes in Body Composition and Nutritional Status in Patients Undergoing Liver Transplantation
- Conditions
- Liver Cirrhosis
- Registration Number
- NCT02023190
- Lead Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Brief Summary
Liver transplant is the goal treatment for every patient with end-stage chronic liver disease.
Quality of life improves after transplant because the main complications of end-stage liver disease disappear, but due to immunosuppression other alterations appear such as metabolic alterations, weight gain, among others.
Body composition and nutritional status can be affected do to post-transplant pharmacologic therapy.
- Detailed Description
Body composition and nutritional status can be affected due to post-transplant pharmacologic therapy.
This is a prospective cohort study, patients from liver transplant waiting list will be assessed, pre and post-transplant measures of body composition and nutritional status will be obtained.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
- Liver cirrhosis (any etiology)
- Enrolled in waiting list for tliver transplant
- Hepatocellular carcinoma
- Chronic renal failure
- Congestive cardiac failure
- Extremity amputation
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Body composition Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant Body composition will be assessed through bioelectrical impedance vector analysis graph.
- Secondary Outcome Measures
Name Time Method Liver function tests Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant
Trial Locations
- Locations (1)
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
🇲🇽Mexico City, DF, Mexico