SAFETY AND FEASIBILITY OF INTRACORONARY HYPOTHERMIA IN ACUTE MYOCARDIAL INFARCTION (SINTAMI) - SINTAMI

Catharina-ziekenhuis0 个研究点目标入组 10 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Patients will be eligible for this study when they are admitted for acute ST elevation myocardial infarction with a total ST-segment deviation of more than 5 mm and presenting within 6 hours after onset of complaints.
•Patients should have a TIMI 0, 1 or 2 flow in the infarction related artery.
•If these patients are hemodynamically stable and in an acceptable clinical condition, informed consent will be asked to participate in this study.

•Age < 18 year
•Cardiogenic shock or pre-shock
•Poor clinical condition with concomitant inconvenience like repeated vomiting, severe chest pain or elsewise according to the judgement of the treating interventionalist.
•Patients with previous myocardial infarction in the culprit area of with previous bypass surgery
•Tortuous coronary arteries
•Complex or long-lasting primary PCI expected
•Severe concomitant disease or conditions with a life expectancy of less than one year
•Inability to understand and give informed consent either in first instance on the table or in second instance on the coronary care unit.
•Other known myocardial diseases, such as moderate or severe left ventricular hypertrophy or cardiomyopathy
•Pregnancy
•Mobitz II block, trifascicular block, or total AV block
•Patients in whom no access to the coronary circulation can be obtained by the
•femoral artery or in whom femoral access was problematic

发起方