MedPath

Comparison of Sleep Disordered Breathing Events Detected by the CPAP Device "prismaLine" With Polysomnography

Not Applicable
Completed
Conditions
Sleep Apnea Syndromes
Interventions
Other: CPAP Treatment
Registration Number
NCT04407949
Lead Sponsor
Institut für Pneumologie Hagen Ambrock eV
Brief Summary

Evaluation of residual sleep disordered breathing (SDB) under continuous positive airway pressure (CPAP) therapy with comparison of the automatic detected SDB event indices from CPAP machines with manual scored polysomnography (PSG).

Detailed Description

The evaluation of residual sleep disordered breathing (SDB) in sleep apnea (SA) after initiation of continuous positive airway pressure (CPAP) therapy is important to verify the therapeutic success. In clinical practice, the internal records of CPAP devices are utilized to determine the therapeutic success, during either medical consultations or telemetric observation.

This study was designed to evaluate the quality of SDB Event Indices (EI), which are recorded by the CPAP device (Prisma, Löwenstein Medical Technology).

The detected events of a manual scored polysomnography (PSG) in the sleep laboratory will be compared with the simultaneously recorded events of the CPAP device.

This shall lead to recommendations regarding the situations, and in which degree the event detection of the CPAP devices may be meaningful to determine the therapeutic success of home sleep apnea therapy.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70
Inclusion Criteria
  • PSG diagnostic not older than 3 month,
  • AHI>15, CPAP indication,
  • age >18,
  • nasal CPAP mask,
  • written informed consent
Exclusion Criteria
  • CPAP contraindication,
  • participation in another clinical trial

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
event detectionCPAP Treatment-
Primary Outcome Measures
NameTimeMethod
apnea- hypopnea- index (AHI)up to 8 hours

Total number (N) and index (N/h) of sleep disordered breathing events (apnoeas plus hypopneas) from PSG and device log

Secondary Outcome Measures
NameTimeMethod
central and obstructive hypopnea indexup to 8 hours

total number (N) and Index (N/h) of hypopneas scored under AASM criteria for central and obstructive hypopneas.

hypopnea index relating to oxygen desaturationup to 8 hours

total number of Hypopneas (N) and Index (N/h) scored under AASM criteria for hypopneas, both rules. 1A: hypopnea events with \>= 3% oxygen desaturation and 1B: hypopnea events with \>= 4% oxygen desaturation.

Trial Locations

Locations (1)

Kliniken Essen-Mitte, Evang. Huyssens-Stiftung/Knappschaft gGmbH

🇩🇪

Essen, NRW, Germany

© Copyright 2025. All Rights Reserved by MedPath