Variable Resistance Training in Patients With Osteoarthrosis of the Knee

Not Applicable

• Conditions: Resistance Training
• Interventions: Other: Conventional strength training; Other: Variable load training

• Registration Number: NCT03722277
• Lead Sponsor: University College South Denmark

Brief Summary

This is a randomized controlled trial investigating the effect of variable load training in patients with knee osteoarthrosis.

The intervention will consist of resistance training with variable load in knee extension- and flexion. The control group will receive conventional strength training with rubber band.

Outcome measures will be the Knee Osteoarthrosis Outcome Score, functional capacity measured in a sit to stand test, 30m. pace walk and a 9 step stair climb test. Additionally isometric strength in knee flexion- and extension will be measured.

Detailed Description

Not available

Study Timeline

• Status Verified: 2018-10
• Study First Submitted: 2018-10-18
• Study Start: 2018-10-22
• Study First Submitted QC: 2018-10-25
• Last Update Submitted: 2018-10-25
• Study First Posted: 2018-10-26
• Last Update Posted: 2018-10-26
• Primary Completion: 2019-12-31
• Study Completion: 2020-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Knee pain and minimum three of the following
• >50 years
• morning stiffness < 30 min
• crepitation
• bone tenderness
• bone osteophytes
• absence of inflammation

Exclusion Criteria

• Other causes of symptoms to the knee

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional strength training	Conventional strength training	The participants will be training two times per week in 10 weeks. Training will consist of a training programme consisting of strength training with rubber bands for hip and knee.
Variable load training	Variable load training	The participants will be training two times per week in 10 weeks. Training will consist of variable load training in knee flexion- and extension. Training will be based on symptoms in isometric strength at five different angles of flexion- and extension.

Primary Outcome Measures

Name	Time	Method
Change in self reported knee function	At baseline and 10 weeks follow up	Knee Osteoarthrosis Outcome Score (100-0, 100 indicating no symptoms and 0 indicating extreme symptoms)

Secondary Outcome Measures

Name	Time	Method
Change in functional capacity	At baseline and 10 weeks follow up	9 step stair climb test
Change in isometric strength	At baseline and 10 weeks follow up	Isometric strength in knee flexion- and extension