Can pharmacological stress test at MRI of the heart improve the detection of coronary stenoses/Kan belastningsprov i magnetkamera ge förbättrad diagnostik av kranskärlsförträngningar? - Infarct_MRI_dobutamine

Conditions: Patients in the first week post myocardial infarction are referred for early coronary angiography. Often, balloon dilatation is performed at the time of angiography. It is debatable which stenoses need dilatation and we would like to improve on the pre-cath information available by performing stress-MRI, using dobutamin as a physiological adjunct, in addition to infarct sizing with the late enhancement method (MRI).

Registration Number: EUCTR2005-001530-32-SE

Lead Sponsor: Jan Engvall

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Authorised-recruitment may be ongoing or finished

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients referred for coronary angiography within 7 days of hospital treatment for acute myocardial infarction, regardless of ST-elevation och non-ST-elevation infarction.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Usual contraindications for MRI, i.a. pacemaker/ICD, intracranial clips, claustrophobia, not willing to participate

Study & Design

Study Type: Interventional clinical trial of medicinal product

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Evaluate the best method to determine whether or not viability is present in an area of infarction.;Secondary Objective: ;Primary end point(s): Wall motion score recorded at echocardiography 3 months post intervention.

Secondary Outcome Measures