Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.

Not Applicable

Withdrawn

• Conditions: Tobacco Retraining of Automatic Approach; Placebo Task
• Interventions: Behavioral: TRAA intervention

• Registration Number: NCT01902199
• Lead Sponsor: University of British Columbia

Brief Summary

A randomized control trial evaluating a novel smoking cessation intervention in individuals at a an inpatient clinic for clients with addiction and concurrent disorders. The intervention is based on cognitive bias modification, where participants are explicitly or implicitly trained to make avoidance movements by pushing a joystick in response to pictures of smoking, and as a result altering their cognitive biases towards smoking and tobacco dependence.

Hypothesis: Participation in the experimental (tobacco-avoidance) condition will induce reduction of smoking, assessed as lower levels of carbon monoxide measured at baseline and 12 week follow-up.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-07-15
• Study First Submitted QC: 2013-07-17
• Study First Posted: 2013-07-18
• Study Start: 2014-10
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-18
• Last Update Posted: 2021-06-22

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Proficiency to read and write english
• A minimum score of 5 or higher on the fagerström test for nicotine dependence, indicating a medium dependence
• Current smoking will be validated by Carbon monoxide breath monitor

Exclusion Criteria

• Patients not yet stabilized enough to allow for regular participation in the intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TRAA	TRAA intervention	participants will be given the active TRAA intervention where landscape images are linked with a push motion, and portrait images linked with a pull motion. Pictures will exclusively be related to smoking.
Control	TRAA intervention	participants will be given a mix of landscape and portrait pictures, equally divided into push or pull. the images will be a mix of smoking related pictures and non smoking pictures.

Primary Outcome Measures

Name	Time	Method
Carbon monoxide levels in breath	baseline, 12 weeks	The breath carbon monoxide monitoring device will be used both before the intervention for a baseline measure and at the 12-week follow-up for comparison. These two measurements will be used to detect changes in smoking patterns that may have occurred during this interval. The method allows to objectify abstinence from smoking.

Secondary Outcome Measures

Name	Time	Method
Fagerström test for Nicotine dependence (FTND)	Baseline	The FTND is a 6-item questionnaire scored to test level of nicotine dependence, and will be presented to patients prior to the intervention. Patients meeting a cut-off score of 5 or higher will be eligible to participate in the intervention portion of this study.

Trial Locations

Locations (1)

Burnaby Centre for Mental Health and Addiction; 🇨🇦 Burnaby, British Columbia, Canada