Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules

Not yet recruiting

• Conditions: Thyroid Nodules; Pulsed Field Ablation

• Registration Number: NCT07226804
• Lead Sponsor: M.D. Anderson Cancer Center

Brief Summary

To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.

Detailed Description

Primary Objectives

• To evaluate the thyroid nodule volume changes over time in participants undergoing nsPFA as part of routine clinical care

Secondary Objectives

* To determine changes in health-related quality of life changes following ultrasound-guided nsPFA

* To evaluate the ultrasound features of thyroid nodules over time following ultrasound-guided nsPFA.

* To assess the incidence and nature of complications following ultrasound-guided nsPFA, categorized into Minor and Major complications.

Study Timeline

• Status Verified: 2025-11
• Study First Submitted: 2025-11-07
• Study First Submitted QC: 2025-11-07
• Last Update Submitted: 2025-11-07
• Study First Posted: 2025-11-10
• Last Update Posted: 2025-11-10
• Study Start: 2026-04-26
• Primary Completion: 2028-08-31
• Study Completion: 2030-08-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality-of-life Questionnaire	Through study completion; an average of 1 year

Trial Locations

Locations (1)

MD Anderson Cancer Center; 🇺🇸 Houston, Texas, United States