The need for Antibiotic Prophylaxis Therapy in the Extraction of third molars from healthy patients
- Conditions
- Surgical site infecctionC23.550.767
- Registration Number
- RBR-10gcjj55
- Lead Sponsor
- Faculdade de Odontologia da Universidade Federal de Uberlândia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Volunteers aged 18 and over; both genders; with at least 1 mandibular third molar to be extracted under local anesthesia - indications for extraction in this study will be any third molar, impacted or not, with or without limited space for eruption, or extraction indicated for any other reason in accordance with the criteria from the Oral and Maxilo Facial Surgery Department (CTBMF)
Age under 18; poor oral conditions; pregnant women; systemic illnes; inflammation or infection at the extraction sites; current use of other antibiotic therapy; immunosuppression; gastrointestinal bleeding or ulceration; cardiovascular and kidney diseases; and any allergies to the local anesthetic (Alphacaine 100, DFL, Brazil - 2% Lidocaina HCl with 1:100,000 Epinephrine); Nimesulide or other nonsteroidal anti-inflammatory drugs
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluating the infection level after third molars extraction by using different medicin terapeutics in the experimental groups; from data listed in the Formulary I evaluations will be made within and/or among the groups; unnecessary use of antibiotic prophylaxis before or after surgical proceeding is expected; statistical analysis with 5% confidence level will be performed
- Secondary Outcome Measures
Name Time Method Secondery effects are not expected