Presence of IBD Specific Antibodies (ASCA, ALCA, ACCA, AMCA) in the Sera of Patients With Spondyloarthropathy

• Conditions: Psoriatic Arthritis; Ankylosing Spondylitis; Undifferentiated Spondyloarthropathy

• Registration Number: NCT00517101
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

A relationship between IBD and spondyloarthropathy is well recognized. ASCA ( anti saccharomyces cerevisiae antibodies)are considered to be a serological marker for Crohn's disease and have been studied in patients with spondyloarthropathy with conflicting results. More recently, new serological markers for IBD have been described. These markers are antibodies to certain defined glycans , and their use may permit an improved diagnosis of IBD.

The aim of our study is to investigate wether these new serological markers are present in the sera of patients with spondyloarthropathy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2007-08
• Study First Submitted: 2007-08-15
• Study First Submitted QC: 2007-08-15
• Last Update Submitted: 2007-08-15
• Study First Posted: 2007-08-16
• Last Update Posted: 2007-08-16
• Study Start: 2007-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• diagnosis of psoriatic arthritis, ankylosing spondylitis, or undifferentiated spondyloarthropathy

Exclusion Criteria

• diagnosed inflammatory bowel disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified