NCT00005629已完成1 期
Phase I/II Trial Testing Alpha Fetoprotein (AFP) Peptide Immunization in Hepatocellular Carcinoma
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 6
- 试验地点
- 2
- 主要终点
- Safety
研究概览
简要总结
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness of vaccine therapy in treating patients who have liver cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Safety
时间窗: 1 month
Determine the safety of intradermal injection of the hAFP137-145 (PLFQVPEPV), hAFP158-166 (FMNKFIYEI), hAFP325-334 (GLSPNLNRFL) and hAFP542-550 (GVALQTMKQ) peptides emulsified in Montanide ISA-51.
次要结局
- antigen-specific immune response(1 month)
- Survival(1 month)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
Vaccine Therapy in Treating Patients Who Have Stage II, Stage III, or Stage IV MelanomaMelanoma (Skin)NCT00010309Genzyme, a Sanofi Company
已完成
2 期
Vaccine Therapy in Treating Patients With Recurrent Soft Tissue SarcomaSarcomaNCT00005628Memorial Sloan Kettering Cancer Center
已完成
2 期
Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the LiverMetastatic CancerColorectal CancerNCT00033748Alliance for Clinical Trials in Oncology56
撤回
1 期
Vaccine Therapy in Treating Patients With Metastatic or Recurrent CancerUnspecified Adult Solid Tumor, Protocol SpecificBreast CancerLung CancerOvarian CancerGastric CancerNCT00017537University of Alabama at Birmingham
Unknown
2 期
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With SurgeryMelanoma (Skin)NCT00086866European Organisation for Research and Treatment of Cancer - EORTC165