Prevention Chemotherapy Induced Mucositis by Zinc Sulfate
Phase 2
Completed
- Conditions
- MucositisBone Marrow Transplantation
- Interventions
- Drug: Placebo
- Registration Number
- NCT01015183
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
In this double blinded randomized study we evaluate effect of Zinc sulfate for prevention mucositis due to high dose chemotherapy in the patients undergoing bone marrow transplantation whose received Busulfan and/or Cyclophosphamide. Patients randomized in two groups: intervention and control with balanced block randomization method. Intervention group received Zinc sulfate immediately after start conditioning regimen and continued for two weeks. Control group received placebo at the same manner. Prevalence and severity of mucositis will be compared in two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Patient undergoing bone marrow transplantation
- Signed informed consent
Exclusion Criteria
- Unable take drug (or placebo) orally
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention Zinc Sulfate Received Zinc Sulfate Control Placebo Control group
- Primary Outcome Measures
Name Time Method The effect of Zinc Sulfate on prevention of mucositis in patients undergoing bone marrow transplantation 1 year
- Secondary Outcome Measures
Name Time Method Evaluation of Zinc Sulfate concentration 1 year Evaluation of Zinc Sulfate advance effects 1 year
Trial Locations
- Locations (1)
Hematology-Oncology & SCT Research Center
🇮🇷Tehran, Iran, Islamic Republic of