A high-fat meal challenge study exposing non-traditional risk factors for Type 2 Diabetes for Chinese Australians

Not Applicable

• Conditions: Type 2 Diabetes Mellitus; Cardiovascular Diseases; Metabolic and Endocrine - Diabetes; Cardiovascular - Other cardiovascular diseases; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12620001365954
• Lead Sponsor: Catherine Huggins

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-18
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Group 1: Adult migrants of Chinese ethnicity who screen at high risk of T2D according to the AUSDRISK tool.

Group 2:Adult Caucasians who screen at high risk of T2D according to the AUSDRISK tool

Exclusion Criteria

A confirmed diagnosis of T2D or a diagnosis of lipid-related disorder (e.g hypercholesterolemia, fatty liver); anyone on lipid lowering medication or other medications and smokers known to interfere with normal lipid metabolism.
Participants with abnormal fasting triglycerides and fasting glucose above 7mmol/L(this is indicative of diabetes)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be the difference in the postprandial triglycerides incremental area under the curve (iAUC) between the two groups. This will be assessed based on plasma blood samples taken over the 6 hours postprandial for each participant.[The entire 6 hours period after ingestion of the first test meal for each study visit<br><br>Twelve blood samples will be taken at baseline, 15, 30, 45, 60, 90. 120. 180, 240, 270, 300, and 360 minutes post ingestion..]