An evaluation of platelet activation and function in different haematological disorders pre and post treatment using flow cytometry and extracellular regulatory kinase pathway
Not Applicable
Withdrawn
- Conditions
- Platelet activation and function pre and post treatment in haematological disordersBlood - Haematological diseases
- Registration Number
- ACTRN12610000313033
- Lead Sponsor
- aunceston General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients including those with malignant haematological disorders e.g. leukaemia, lymphoma and multiple myeloma will be recruited on a voluntary basis over a period of 3 years. While age and sex matched controls will be chosen as healthy volunteers as well as patients without any haematological disorders.
Exclusion Criteria
Women who are pregnant and the human
foetus
Children and/or young people (ie. <18 years)
People in existing dependent or unequal
relationships
People with a cognitive impairment, an
intellectual disability or a mental illness
People who may be involved in illegal activity
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Platelet function will be assessed by flow cytometry[Before the treatment (at time of diagnosis of the disease) as a baseline investigation as well as 30, 60, 90 and 150 days from start of treatment]
- Secondary Outcome Measures
Name Time Method Association between platelet dysfunction and different haematological disorders[6 months post recruitment]