Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

Not Applicable

Completed

• Conditions: Abdominal Obesity
• Interventions: Other: Resistance Exercise (RE); Other: Aerobic Exercise (AE); Other: Resistance and Aerobic Exercise (RAE)

• Registration Number: NCT00520858
• Lead Sponsor: Queen's University

Brief Summary

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09
• Study First Submitted: 2007-08-24
• Study First Submitted QC: 2007-08-24
• Study First Posted: 2007-08-27
• Status Verified: 2008-04
• Last Update Submitted: 2008-04-21
• Last Update Posted: 2008-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 145

Inclusion Criteria

• Men and women between 65 and 80 years of age.
• Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
• We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion Criteria

• Smokers and diabetics.
• Women taking hormone replacement therapy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
RE	Resistance Exercise (RE)	Resistance Exercise
AE	Aerobic Exercise (AE)	Aerobic Exercise
RAE	Resistance and Aerobic Exercise (RAE)	Resistance and Aerobic

Primary Outcome Measures

Name	Time	Method
Abdominal obesity	6 months

Secondary Outcome Measures

Name	Time	Method
Insulin Resistance	6 Months

Trial Locations

Locations (1)

Queen's University; 🇨🇦 Kingston, Ontario, Canada