A STUDY TO ASSESS THE EFFICACY OF HOMOEOPATHIC MEDICINES SELECTED USING THE RHEUMATIC REMEDIES REPERTORY IN THE MANAGEMENT OF PRIMARY KNEE OSTEOARTHRITIS AMONG POSTMENOPAUSAL WOMEN BY WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 55
- 试验地点
- 1
研究概览
简要总结
Osteoarthritis of the knee is a chronic degenerative joint disorder that causes progressive pain stiffness and functional limitation especially in postmenopausal women Conventional management focuses on pain relief and joint protection but may not address individual susceptibility or constitutional factors Homoeopathy aims to restore balance by prescribing individualized medicines based on the totality of symptoms The Rheumatic Remedies Repertory by HA Roberts is a specialized repertory emphasizing musculoskeletal conditions, offering a structured approach to remedy selection in rheumatic and degenerative diseases
objectives
To assess the efficacy of individualized homoeopathic medicines selected using the Rheumatic Remedies Repertory in managing primary knee osteoarthritis among postmenopausal women using the Western Ontario and McMaster Universities Osteoarthritis Index WOMAC as an outcome measure
methods
This is a prospective, single-arm, interventional clinical study conducted at the Department of Repertory and case taking, AM Shaikh Homoeopathic Medical College Hospital p g and research centre belagavi A total of 55 postmenopausal women aged 45–65 years diagnosed with primary knee osteoarthritis will be enrolled after informed consent Each participant will undergo detailed case taking and repertorization using the Rheumatic Remedies RepertoryIndividualized homoeopathic medicines will be prescribed in suitable potencies 30C or 200C or 1M and followed up monthly for 6 months No comparator or placebo arm will be used
outcome
Improved The Western Ontario and McMaster Universities Osteoarthritis Index score below 60 indicates the improvement in the case after intervention
Not improved The Western Ontario and McMaster Universities Osteoarthritis Index score above 60 indicates not improvement in the case after intervention
analysis
Pre- and post-intervention WOMAC scores will be analyzed using paired t-test or non-parametric equivalent, with p < 0.05 considered statistically significant.
results:
The study is expected to demonstrate measurable improvement in WOMAC scores, reflecting reduction in pain, stiffness, and improved joint function, thereby supporting the role of individualized homoeopathic medicines selected via Rheumatic Remedies Repertory in managing primary knee osteoarthritis among postmenopausal women
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 45.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •1 Postmenopausal women with the age group 45to 65 years 2 Clinically diagnosed cases of primary knee osteoarthritis with American College of Rheumatology clinical classification criteria 3 Subjects willing to sign on consent form 4 Women of all kind of occupations.
排除标准
- •1 Subjects currently undergoing other alternative treatments for osteoarthritis of knee 2 Subjects who are undergoing hormonal therapies 3 Subjects who have undergone knee joint replacement surgery 4 Subjects with Comorbidities such as Diabetes Hypertension and other systemic disorders 5 History of any trauma like fractures ligaments and tears 6 Subjects diagnosed with rheumatoid arthritis or any type of inflammatory arthritis like psoriatic arthritis infective arthritis.
研究者
DR DEVIREDDY MADHURI REDDY
A M SHAIKH HOMOEOPATHIC MEDICAL COLLEGE HOSPITAL AND PG RESEARCH CENTER