Effect of Ketamine and Ondansetrone in reducing propofol injection pai
Phase 3
- Conditions
- Propofol Injection Pain.Parenteral anesthetics
- Registration Number
- IRCT201605144923N7
- Lead Sponsor
- Vice-Chancellor of Research Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
18 to 60 year old ; ASA class 1 or 2 ; candidate for general anesthesia Exclusion criteria: pain at the injection site before injection of study drugs or propofol ; sensitivity to each of study drugs ; anxiety ; lack of cooperation ; history of seizure ; history of cardiovascular disease ; history of psychiatric disorders
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Degree of pain. Timepoint: seconds: 0, 30 and 60. Method of measurement: VAS.
- Secondary Outcome Measures
Name Time Method Bradycardia. Timepoint: Before propofol injection,1min after propofol injection,immediately before and after intubation,5,10 and 15 min after intubation. Method of measurement: Before propofol injection,1min after propofol injection, immediately before and after intubation, 5,10 and 15 min after intubation.;Hypotension. Timepoint: Before propofol injection, 1min after propofol injection, immediately before and after intubation, 5, 10 and 15 min after intubation. Method of measurement: Before propofol injection, 1min after propofol injection, immediately before and after intubation, 5, 10 and 15 min after intubation.