The effect of duration of nonabsorbable nasal packing (merocel) soaked with oxytetracycline and hydrocortisone (terrracortril) in the post-operative management of functional endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) on healing of the sinus cavity
Completed
- Conditions
- nasal polypssinus inflammation10038737
- Registration Number
- NL-OMON42966
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
patients aged ><=18 years, symmetrical crswnp, in whom bilateral primary or revision endoscopic ethmoidectomy is performed due to failure of medical treatment. Intervention on other paranasal sinuses (with the exception of extensive frontal sinus intervention (Draf 3) and correction of septal deviation as part of the study procedure shall be allowed when necessary
Exclusion Criteria
Patients dependent on oral CS and patients who took oral CS from 30 days before the surgery. Patients with cystic fibrosis, antrochoanal polyp, inverted papilloma and vasculitis. Patients with known hypersensitivity to any component of Terracortril will be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Ethmoid inflammation<br /><br>Mean difference in ethmoid inflammation and polyp score (graded in a visual<br /><br>analog scale 0 to 100 mm) between two sides on day 30 (± 7 days). </p><br>
- Secondary Outcome Measures
Name Time Method