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Evaluation of PCO2 and PO2 Values in the Pulmonary Artery and Superior Vena Cava

Completed
Conditions
Heart Diseases
Registration Number
NCT03591029
Lead Sponsor
Catholic University of the Sacred Heart
Brief Summary

The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a PO2 gap, different from zero. Moreover the investigators want to find out if these gaps are related with changes in the cardiac output, the hematocrit or if they can predict post operative dysfunctions.

Blood samples will be taken at six different times as scheduled by the protocol. Along with the two venous blood samples, an arterial blood sample will be taken too, from a radial of femoral artery catheter.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • age > 18 years
  • patient undergoing cardiac surgery with extracorporeal circulation
  • hemodynamic monitoring with a central venous catheter and a Swan Ganz catheter placed in the internal left giugulare vein
Exclusion Criteria
  • severe tricuspid insufficiency
  • EF < 50%
  • SOFA score >1 in at least one of all the criteria

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
PCO2 gap changestwo days

See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery

PO2 gap changestwo days

See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Francesca Bevilacqua

🇮🇹

Rome, Italy

catholic University of the sacred Heart

🇮🇹

Rome, Italy

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