ACTRN12620000764932
Not yet recruiting
未知
Effect of Aggressive vs. Lenient Blood Pressure Control in Patients with Ventricular Tachycardia (VT) on Future VT and Death
Sachin Nayyar0 sites120 target enrollmentJuly 27, 2020
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Sachin Nayyar
- Enrollment
- 120
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age 18\-year to 80\-years.
- •2\. Heart failure due to ischemic or non\-ischemic etiology of more than 3 months duration.
- •3\. Left ventricular ejection fraction \<40%.
- •4\. History of spontaneous sustained VT.
- •5\. Have an implantable cardioverter defibrillator (ICD) or consent to have one.
- •6\. NYHA Class 1 \-3\.
Exclusion Criteria
- •1\.VT related hospitalization within the last 3 weeks.
- •2\.VT ablation in last 3 months.
- •3\.Heart failure NYHA Class 4 or heart failure hospitalization within the last 3 weeks.
- •4\.Resting systolic BP \< 90mmHg at lowest doses of heart failure medication.
- •5\.History of symptomatic systolic BP drop on standing.
- •6\.Exercise induced systolic BP \> 180mmHg or \<90mmHg.
- •7\.Known secondary cause of hypertension.
- •8\.eGFR less than 30ml/min.
- •9\.Intolerance to beta\-blocker (equivalent to Metoprolol 12\.5mg BD) (due to worsening of hypotension or heart failure).
- •10\.Left ventricular ejection fraction \<10%.
Outcomes
Primary Outcomes
Not specified
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