Measurement of Mean Systemic Filling Pressure & Stressed Volume with CardioQ+® Oesophageal Doppler Measurement

Completed

Conditions: Hemodynamic instability
Geavanceerde hemodynamische monitoring bij hemodynamische instabiliteit obv verschillende oorzaken zoals cardiogene shock, etc.
shock

Registration Number: NL-OMON47434

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 42

Inclusion Criteria

- Patients planned for elective CABG surgery
- Aged 18 years and over
- Being able to give written informed consent prior to surgery

Exclusion Criteria

- A contraindication for fluid loading (700ml) assessed by the treating ICU physician.
- Pregnancy
- Morbid obesity (BMI >40)
- Major hemodynamic instability with a mean arterial pressure (MAP) < 55 mmHg, a cardiac index < 1.5 L·min-1 or right heart failure
- Severe arrhythmias
- Intra-cardiac shunts
- Symptomatic peripheral vascular disease
- Symptomatic pulmonary disease
- Significant valvular regurgitation
- A poor left or right ventricular function
- Contra-indication for rapid cuff inflation, in case of:
* shunt-arm
* lymph-node excision
* skin laesions
- Contra-indication to oesophageal Doppler probe insertion, in case of:
* Nasal injuries
* Nasal polyps
* Facial trauma
* Intra-aortic balloon pump therapy
* Carcinoma of the pharynx, larynx or oesophagus
* Aneurysm of the thoracic aorta
* Severe coagulopathy or thrombocytopenia
* After oesophageal surgery
* (Suspected) oesophageal disease

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In this study fluid loading responsiveness after 500 mL fluid, and stressed<br /><br>volume measurement before and after 500 mL fluid administration are the main<br /><br>outcome measures. </p><br>

Secondary Outcome Measures