Association of Protein Intake With Sarcopenia Among Institutionalized Elderly

Completed

• Conditions: Protein Deficiency; Sarcopenia

• Registration Number: NCT04685382
• Lead Sponsor: Indonesia University

Brief Summary

This study has purpose to investigated the association of protein intake with sarcopenia in the institutionalized elderly at south tangerang

Detailed Description

Data were collected using interview with subjects or with care giver to know the basic characteristic of subjects. Anthropometric measurements were done body weight in kilograms was measured using SECA scale. Body height in meters was predicted by knee height measurement using knee height caliper. Body mass index (BMI) was calculated as weight per height square. Fat free mass was examined using bioelectrical impedance analyzer Tanita type SC-330. Independency was assessed using Barthel index. Protein intake was measured using 2x24 hour food recall and analyzed using a computer program Nutrisurvey 2007, data were compare to Recommended Dietary Allowances established for Indonesian 2018. Handgrip muscle strength was examined using Jamar handgrip dynamometer. Physical performance was measured using Short Physical Performance Battery test. Sarcopenia was diagnosed using Asian Working Group on Sarcopenia.

All data collected were analyzed using Statistical Package for the Social Science (SPSS) version 20 for windows. Nominal data were described using frequency, n (%). Normality of data was tested using Kolmogorov-Smirnov test with normal distribution (p\>0.05) described using mean and SD while not normal distribution (p\<0.05) described using median and range minimum-maximum. The investigators used Independent T-test analysis to investigate the association.

Study Timeline

• Study Start: 2019-05-20
• Primary Completion: 2019-05-30
• Study Completion: 2019-05-30
• Status Verified: 2020-12
• Study First Submitted: 2020-12-14
• Study First Submitted QC: 2020-12-21
• Last Update Submitted: 2020-12-21
• Study First Posted: 2020-12-28
• Last Update Posted: 2020-12-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Inclusion criteria were being male or female
2. aged more than 60 years old
3. signed inform consent form and literate with help from companion

Exclusion Criteria

1. subjects with history of cancer
2. history of upper and lower extremities weakness
3. history of chronic heart failure disease
4. chronic obstructive pulmonary disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Characteristic of fat free mass subject	After signing the consent	to examine fat free mas of the subject using bioelectrical impedance analyzer Tanita type SC-330 and classified by Asian gender and aged Male : Normal 53,30±4,79 kg Female : Normal 37,96±3,41 kg
Protein intake of the subject	After signing the consent	to assessed protein intake of the subject using 2x24 hour food recall and analyzed using a computer program Nutrisurvey 2007, data were compare to Recommended Dietary Allowances established for Indonesian 2018
Distribution of sarcopenia subject in the institutionalized elderly	After signing the consent	to investigate the distribution of sarcopenia subject using Asian Working Group Of Sarcopenia for diagnostic (fat Free Mass, handgrip strength,physical performance) Sarcopenia categorized low muscle mass (fat free mass) and either low muscular strength or low physical performance
Characteristic of handgrip strength subject	After signing the consent	to assessed handgrip strength of the subject using Jamar handgrip dynamometer, assessment criteria based on the Asian Working Group on Sarcopenia Male : Normal \> 26 kg Female : \> 18 kg
Characteristic of physical performance subject	After signing the consent	to examine physical performance (lower extremity strength) using Short Physical Performance Battery test. Classified using Asian Working Group on Sarcopenia Good physical performance score ≥9
Association of protein intake with sarcopenia	immediately after the procedure	to investigate the association of protein intake with sarcopenia. After protein intake and sarcopenia analysis were completed. The investigators used Independent T-test to analyzed the association protein intake between sarcopenia subject compare to non-sarcopenia subject

Secondary Outcome Measures

Name	Time	Method
Nutritional status of the subjects	After signing the consent	to investigate nutritional status using anthropometric measurements were done body weight in kilograms was measured using SECA scale. Body height in meters was predicted by knee height measurement using knee height caliper. Body mass index (BMI) was calculated as weight per height square (kg/m2). Nutritional status categorized using WHO Asia Pacific body mass index. Categorized: \< 18,5 kg/m2 : underweight 18,5-22,9 kg/m2: normal 23-24,9 kg/m2: overweight \>25 kg/m2: obese 1; ≥30 kg/m2 : obese 2
Barthel index of the subject	After signing the consent	to know independency of the subject using barthel index scoring; Scoring: Independent : 20 Mild Dependency : 12-19 Moderate Dependency : 9-11 Severe Dependency : 5-8 Total : 0-4 Independent, n (%) Mild Dependency, n (%) Moderate Dependency, n (%) Severe Dependency, n (%)

Trial Locations

Locations (1)

Fiastuti Witjaksono; 🇮🇩 Jakarta Pusat, DKI Jakarta, Indonesia