Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia

Phase 4

Terminated

• Conditions: Anesthesia
• Interventions: Drug: succinylcholine; Drug: rocuronium

• Registration Number: NCT01579864
• Lead Sponsor: Hopital Foch

Brief Summary

Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a rapid and complete reversal of the neuromuscular block. The aim of ths study is to compare both agents.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-01-04
• Study First Submitted QC: 2012-04-17
• Study First Posted: 2012-04-18
• Primary Completion: 2015-06
• Study Completion: 2015-06
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-02
• Last Update Posted: 2016-11-03

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

• patients scheduled for an interventional rigid bronchoscopy under general anesthesia

Exclusion Criteria

• pregnant woman or woman of childbearing age,
• morbid obesity,
• drug allergy,contra-indication to succinylcholine, rocuronium, sugammadex, propofol, remifentanil,
• history of central neurological or brain damage,
• psychotropic treatment,
• pacemaker,
• renal failure,
• disease of the neuromuscular junction.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
succinylcholine	succinylcholine	Succinylcholine 1 mg/kg and a second dose if necessary.
Rocuronium	rocuronium	rocuronium 0,9 mg/kg with additional boluses of 0,3 mg/kg f necessary

Primary Outcome Measures

Name	Time	Method
Score of quality of the surgical procedure	one day	The quality of the surgical procedure is evaluated by the surgeon (composite score) who is unaware of the neuromuscular agent used (see Fuchs-Buder et al. Acta Anaesthesiol Scand 2007;51(7):789-808)

Secondary Outcome Measures

Name	Time	Method
Score of quality of anesthesia	one day	The quality of anesthesia is evaluated by the anesthesist in charge on a scale 0-30 (0-10 for the induction ; 0-10 for maintenance; 0-10 for recovery)

Trial Locations

Locations (1)

Hopital Foch; 🇫🇷 Suresnes, Ile de France, France