Interventional Rigid Bronchoscopy Under General Anesthesia: Influence of the Muscle Relaxant, Succinylcholine or Rocuronium, on the Quality of the Surgical Procedure
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- Hopital Foch
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- Score of quality of the surgical procedure
研究概览
简要总结
Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a rapid and complete reversal of the neuromuscular block. The aim of ths study is to compare both agents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for an interventional rigid bronchoscopy under general anesthesia
排除标准
- •pregnant woman or woman of childbearing age,
- •morbid obesity,
- •drug allergy,contra-indication to succinylcholine, rocuronium, sugammadex, propofol, remifentanil,
- •history of central neurological or brain damage,
- •psychotropic treatment,
- •pacemaker,
- •renal failure,
- •disease of the neuromuscular junction.
研究组 & 干预措施
succinylcholine
Succinylcholine 1 mg/kg and a second dose if necessary.
干预措施: succinylcholine (Drug)
Rocuronium
rocuronium 0,9 mg/kg with additional boluses of 0,3 mg/kg f necessary
干预措施: rocuronium (Drug)
结局指标
主要结局
Score of quality of the surgical procedure
时间窗: one day
The quality of the surgical procedure is evaluated by the surgeon (composite score) who is unaware of the neuromuscular agent used (see Fuchs-Buder et al. Acta Anaesthesiol Scand 2007;51(7):789-808)
次要结局
- Score of quality of anesthesia(one day)