NCT05202899Unknown4 期
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy
Guangzhou General Hospital of Guangzhou Military Command1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年9月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- awake time
研究概览
简要总结
Effect of sugammadex for reversal of rocuronium-induced neuromuscular block on Perioperative Management of awake Craniotomy
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-45 years old body mass index (BMI)≥ 18.5-23.9 kg/m2, ASA grade I ~II.
排除标准
- •Suffering from a mental illness or preoperative communication disorder, patients with claustrophobia, breathing, circulation, neuromuscular system and kidney, and other important viscera function disorder, pregnant or lactating women, a history of malignant hyperthermia, the history of drug allergy in the process of general anesthesia and recent may not used to the interaction between rocuronium, vecuronium bromide reacts drugs (such as aminoglycoside antibiotics, Anticonvulsant, magnesium).
研究组 & 干预措施
Sugammadex Group
Experimental
rocuronium-induced general anesthesia，use of sugammadex antagonism
干预措施: sugammadex (Drug)
结局指标
主要结局
awake time
时间窗: 10-30 minutes
The time between asleep and awake
次要结局
未报告次要终点
研究者
bo xu
Clinical Professor
Guangzhou General Hospital of Guangzhou Military Command
研究点 (1)
Loading locations...
相似试验
已完成
不适用
The Effect of Sugammadex Given Based on Ideal, Actual or Adjusted Body Weight on Reversal of Rocuronium.Muscle RelaxationNCT03381209Ain Shams University60
尚未招募
2 期
Sugammadex Dose Finding Under Two Years OldNeuromuscular BlockadeNCT06575036Sang-Hwan Ji33
已完成
4 期
Sugammadex Titration in Cardiac Surgery PatientsValvular Heart DiseaseAorta DiseaseHeart FailureCoronary Artery DiseaseNCT05246397University of Washington100
已完成
3 期
Recovery of Diaphragmatic Function After Neuromuscular Blockade and SugammadexDiaphragmatic DysfunctionMuscle WeaknessMuscle FatigueNCT01962298University Hospital, Antwerp75
撤回
4 期
Impact of iv Dexamethasone on Reversal of Rocuronium-induced Neuromuscular Block by SugammadexNeuromuscular BlockadeNCT02562417Centre Hospitalier Universitaire Vaudois