NCT05202899
Unknown
Phase 4
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy
Guangzhou General Hospital of Guangzhou Military Command1 site in 1 country40 target enrollmentStarted: September 1, 2020Last updated:
Overview
- Phase
- Phase 4
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- awake time
Overview
Brief Summary
Effect of sugammadex for reversal of rocuronium-induced neuromuscular block on Perioperative Management of awake Craniotomy
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age: 18-45 years old body mass index (BMI)≥ 18.5-23.9 kg/m2, ASA grade I \~II.
Exclusion Criteria
- •Suffering from a mental illness or preoperative communication disorder, patients with claustrophobia, breathing, circulation, neuromuscular system and kidney, and other important viscera function disorder, pregnant or lactating women, a history of malignant hyperthermia, the history of drug allergy in the process of general anesthesia and recent may not used to the interaction between rocuronium, vecuronium bromide reacts drugs (such as aminoglycoside antibiotics, Anticonvulsant, magnesium).
Arms & Interventions
Sugammadex Group
Experimental
rocuronium-induced general anesthesia，use of sugammadex antagonism
Intervention: sugammadex (Drug)
Outcomes
Primary Outcomes
awake time
Time Frame: 10-30 minutes
The time between asleep and awake
Secondary Outcomes
No secondary outcomes reported
Investigators
bo xu
Clinical Professor
Guangzhou General Hospital of Guangzhou Military Command
Study Sites (1)
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