Sevoflurane, Propofol, Postoperative Pain

Phase 4

Completed

• Conditions: Healthy Adults; Gynecological Disease

• Registration Number: NCT01437462
• Lead Sponsor: Tampere University Hospital

Brief Summary

The impact of anaesthetic method (intravenous vs. inhalational) has been proposed, but not proven in a large-scale study. The researchers aim to provide an investigation that has sufficient power to clarify the potential effect of anaesthetic method on postoperative need of opioids. Sevoflurane and propofol will be compared.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-10
• Study First Submitted: 2011-09-19
• Study First Submitted QC: 2011-09-19
• Study First Posted: 2011-09-21
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2013-04
• Last Update Submitted: 2013-04-09
• Last Update Posted: 2013-04-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 168

Inclusion Criteria

• Age 18-69 years
• Gender: female
• ASA status 1-3
• Laparoscopic hysterectomy

Exclusion Criteria

• Body Mass Index over 35
• Diabetes mellitus
• Liver disease
• Allergies to pharmaceuticals used in the Study
• Present use of opioids

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Postoperative consumption of an opioid (oxycodone)	20 hours	The consumption of oxycodone will be monitored by recording the amount of the drug received via a commercially available patient controlled analgesia (PCA) pump.

Secondary Outcome Measures

Name	Time	Method
NRS (numeral rating scale) of pain	20 hours	NRS is evaluated frequently during the study period.

Trial Locations

Locations (1)

Tampere University Hospital; 🇫🇮 Tampere, Finland