The effect of probiotic supplementation on cognitive, inflammation and oxidative stress in adults with Alzheimer disease: A randomized, double blind, placebo-controlled trial

Tehran University of Medical Sciences0 个研究点目标入组 30 人开始时间: 待定最近更新: 2021年6月21日

适应症

试验速览

暂无简介。

•Age 80-50 years
•Resident of Tehran
•Diagnosis of Alzheimer's disease according to NINCDS-ARDA criteria maximum in the last 2 years
•BMI=18/5-30 Kg/m2
•Use of acetylcholinesterase inhibitors (AchEIs) and N-methyl dispartate (NMDA) receptor antagonists
•caregivers understands the objectives of the study and agrees to follow the necessary rules throughout the study

•Having frontotemporal dementia, Levy Buddy dementia, Parkinson's disease dementia and any type of severe dementia
•Take antibiotics at least three months before enrollment
•Smoking (at least 5 cigarettes a day for the past 6 months) and other tobacco (pipe and hookah at least once a month
•Any drug addiction
•Follow a specific diet for three months before the study
•People who participated in another study less than two months ago.
•Take any amount of supplements or foods fortified with fins or probiotics during the last 3 months
•History of serious kidney, liver, intestinal, endocrine diseases, cardiovascular, gastrointestinal, pulmonary, blood and metabolic diseases, thyroid, rheumatoid arthritis and lupus
•History of major gastrointestinal surgeries including gastrectomy, bowel restriction, etc.

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