IRCT20210513051277N1
尚未招募
3 期
The effect of probiotic supplementation on cognitive, inflammation and oxidative stress in adults with Alzheimer disease: A randomized, double blind, placebo-controlled trial
概览
- 阶段
- 3 期
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Tehran University of Medical Sciences
- 入组人数
- 30
- 状态
- 尚未招募
- 最后更新
- 4年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Age 80\-50 years
- •Resident of Tehran
- •Diagnosis of Alzheimer's disease according to NINCDS\-ARDA criteria maximum in the last 2 years
- •BMI\=18/5\-30 Kg/m2
- •Use of acetylcholinesterase inhibitors (AchEIs) and N\-methyl dispartate (NMDA) receptor antagonists
- •caregivers understands the objectives of the study and agrees to follow the necessary rules throughout the study
排除标准
- •Having frontotemporal dementia, Levy Buddy dementia, Parkinson's disease dementia and any type of severe dementia
- •Take antibiotics at least three months before enrollment
- •Smoking (at least 5 cigarettes a day for the past 6 months) and other tobacco (pipe and hookah at least once a month
- •Any drug addiction
- •Follow a specific diet for three months before the study
- •People who participated in another study less than two months ago.
- •Take any amount of supplements or foods fortified with fins or probiotics during the last 3 months
- •History of serious kidney, liver, intestinal, endocrine diseases, cardiovascular, gastrointestinal, pulmonary, blood and metabolic diseases, thyroid, rheumatoid arthritis and lupus
- •History of major gastrointestinal surgeries including gastrectomy, bowel restriction, etc.
结局指标
主要结局
未指定
相似试验
已完成
不适用
The effect of probiotic supplementation on cognitive function and inflammatory markers in patients with early and late phases of Alzheimer's diseaseAlzheimer,s disease.IRCT2017061534549N1Kashan University of Medical Sciences60
招募中
2 期
Effect of probiotics in patients with Parkinsons DiseaseHealth Condition 1: G20- Parkinsons diseaseCTRI/2020/03/024021Dept of Science and Technology
招募中
3 期
Effect of probiotic supplementation in patients with type 2 diabetesIRCT20090901002394N44Iran University of Medical Sciences84
招募中
3 期
Effect of Probiotics Supplementation on Cognitive Status, Daily Life Function and Metabolic IndexesCondition 1: Dementia. Condition 2: Alzheimer's disease.Vascular dementiaAlzheimer's diseaseIRCT20191008045024N1Tehran University of Medical Sciences68
已完成
不适用
Effects of probiotics on cognition and mood status in community-dwelling elderlyNot ApplicableKCT0003929Seoul National University96