ChiCTR-RCH-12002823CompletedPhase 1
ABCG2 基因甲基化对瑞舒伐他汀药物代谢动力学的影响
国家自然科学基金1 site in 1 country24 target enrollmentStarted: March 1, 2012Last updated:
Interventions
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- 药物代谢动力学
Study Overview
Brief Summary
ABCG2 中甲基化程度对瑞舒伐他汀药代动力学的影响
Study Design
- Study Type
- 病因学/相关因素研究
- Primary Purpose
- 队列研究
Eligibility Criteria
- Ages
- 18 to 26 (—)
- Sex
- Male
Inclusion Criteria
- •SLCO 1B1 521TT，CYP2C9*1/*1，ABCG2 421CC，ABCG2 34GG，甲基化程度高低
Exclusion Criteria
- •SLCO 1B1 521 位、CYP2C9、ABCG2 421 位、ABCG2 34 位突变型
Arms & Interventions
1
瑞舒伐他汀
Intervention: 瑞舒伐他汀
Outcomes
Primary Outcomes
药物代谢动力学
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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