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Clinical Trials/NCT04724304
NCT04724304
Completed
N/A

Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Mayo Clinic1 site in 1 country115 target enrollmentFebruary 9, 2021
ConditionsHealthy Adults

Overview

Phase
N/A
Intervention
Not specified
Conditions
Healthy Adults
Sponsor
Mayo Clinic
Enrollment
115
Locations
1
Primary Endpoint
Myocardial blood volume
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

Registry
clinicaltrials.gov
Start Date
February 9, 2021
End Date
November 11, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Courtney E. Bennett

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years.
  • Available for testing performed in Rochester, MN.
  • Willing to undergo both an echocardiogram with RTMPE and CMR.
  • Study subject providing consent.

Exclusion Criteria

  • Adults \< 18 years.
  • BMI \<30 kg/m\^
  • Hypertension.
  • Diabetes Mellitus.
  • Cardiomyopathy or structural heart disease.
  • Known coronary artery disease or history of myocardial infarction.
  • Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
  • Renal GFR \< 50 mL/mL.
  • Females who are pregnant.
  • Subject unwilling to consent.

Outcomes

Primary Outcomes

Myocardial blood volume

Time Frame: Baseline

Ratio in systole and diastole (MBVs/MBVd) by real-time myocardial perfusion echocardiography (RTMPE)

Study Sites (1)

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