A Randomized controlled study to evaluate the efficacy on male lower urinary tract symptoms with overactive bladder of alpha 1-adrenoceptor antagonist in monotherapy and combination therapy with Eviprostat
- Conditions
- Male lower urinary tract symptoms with overactive bladder
- Registration Number
- JPRN-UMIN000002782
- Lead Sponsor
- Oita University Faculty of Medicine,Department of Urology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 120
Not provided
1. Patients taking medications considered likely to affect micturition 2. PSA>10ng/ml, Patients who suspected prostate cancer 3. Patients who suspected neurogenic bladder 4. Patients with urethral stricture 5. Patients with chronic prostatitis or active urinary tract infenction 6. Patients with previous surgery for BPH 7.Patients with previous intrapelvic radiation 8. Complications considered likely to affect micturition(bladder neck constriction,bladder calculus,urinary calculus, cerebrovascular disease etc). 9. Patients with severe hepatic disorders,severe renal dysfunction and severe cardiovascular disease 10. Patients with performing intermittent catheter insertion themselves 11. Patients with orthostatic hypotension 12.Patients taking OTC medication and dietary supplement considered likely to affect micturition
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate by using Questionnaires for urinary symptoms(IPSS and OABSS) at 4,8 and 12 weeks.
- Secondary Outcome Measures
Name Time Method