This Study Evaluates the Effect of Scaling and Root planing on GCF and Serum Leptin Levels in Periodontally Healthy, Chronic Periodontitis and Chronic Periodontitis with Type 2 Diabetes Mellitus Patients.

Phase 2

Conditions: Health Condition 1: null- Periodontally healthy patients Chronic periodontitisDiabetes Mellitus with Chronic periodontitis

Registration Number: CTRI/2017/10/010259

Lead Sponsor: VSPM Dental College and Research Institute

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Group 1 Patients with clinically healthy periodontium GI-0, PD less than or equal to 3mm and CAL- 0 with no evidence of bone loss, HbA1c levels less than 6.5 % and RBS levels less than 160 mg/dl

Group II Generalized moderate to severe chronic periodontitis patients with GI greater than or equal to 1, greater than 30% of sites having PPD of greater than or equal to 5mm, positive BOP and CAL of greater than or equal to 5mm with radiographic evidence of bone loss, HbA1c levels less than 6.5 % and RBS levels less than 160 mg/dl

Group III Generalized moderate to severe chronic periodontitis with Type 2 DM patients with GI score greater than 1, greater than 30% of sites having PPD of greater than or equal to 5mm, positive BOP and CAL of greater than or equal to 5mm with radiographic evidence of bone loss, HbA1c levels between 6.5- 8 % and RBS levels greater than 160 mg/dl

Exclusion Criteria

Medical disorders such as cardiovascular or renal disease

Malignancies, multiple sclerosis and

Tobacco chewers and smokers

Pregnant, post-menopausal and lactating females

No history of antibiotic intake within 6 weeks

No history of any periodontal therapy within 6 months