Therapeutic hypercapnia after cardiac arrest: a pilot feasibility and safety randomized controlled trial

Not Applicable

Completed

• Conditions: Cardiac arrest; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12612000690853
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-06-27
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 380

Inclusion Criteria

Non-traumatic, in- or out-of-hospital cardiac arrest with successful resuscitation (return of spontaneous circulation)
- Mechanical ventilation

Exclusion Criteria

- Spontaenous ventilation
- Death considered immiment
- Clinical or Computerized Tomography suspicion of raised intra-cranial pressure
- Cardiac arrest secondary to intracranial bleed
- Pregnancy
- Age <18 years
- Severe chronic airflow limitation
- Severe metabolic acidosis (base deficit > 6 mEq/L)
- Severe acidemia (pH<7.1)
- Transfered from another healthcare facility
- Participation declined by the treating clinician

Study & Design

• Study Type: Interventional
• Study Design: Not specified